The first global systematic review suggests that receiving the shingles vaccine could reduce the risk of heart attack or stroke by up to 18% in adults. Researchers analyzed 19 studies, including randomized trials and observational data, and found the protective effect was present across age groups, with slightly lower benefits in those over 50.
Shingles, caused by the reactivation of the varicella-zoster virus, can trigger inflammation in the body, which is known to contribute to cardiovascular problems. By preventing shingles, the vaccine may indirectly lower this risk. Experts caution, however, that most current evidence is observational, and more research is needed to confirm a direct causal link.
The findings highlight the broader potential benefits of vaccination beyond infection prevention, and NHS England is expanding eligibility for the shingles jab, making it available to more people with weakened immune systems.
